Drug "Streptotsid"
(powder for external use, 2.0 g or 5.0 g

Used in complex therapy for the treatment of purulent wounds, infected burns and other purulent-inflammatory processes of soft tissues.

Registration number:  ЛП-005046

Trade name

Streptocide

International nonproprietary name

Sulfanilamide

Dosage form

powder for external use

Compound

Sulfanilamide (streptocide) – 2.0 g or 5.0 g

Description

white or almost white with a yellowish tint, odorless crystalline powder.

Pharmacotherapeutic group

antimicrobial agent -  sulfonamide.

Code ATH: D06VA05

Pharmacological properties

Streptocide is an antimicrobial bacteriostatic agent. The mechanism of action is due to competitive antagonism with para-aminobenzoic acid (PABA) and inhibition of the enzyme dihydropteroate synthetase, which leads to disruption of the synthesis of dihydrofolic and then tetrahydrofolic acid and, as a result, to disruption of the synthesis of nucleic acids of microorganisms. Activity is manifested against gram-positive and gram-negative microorganisms.

Indications for use

As part of complex therapy: purulent wounds, infected burns (I-II degrees) and other purulent-inflammatory processes of the skin.

Contraindications

Hypersensitivity to sulfonamides. Pregnancy, breastfeeding period. Diseases of the hematopoietic system, inhibition of bone marrow hematopoiesis, anemia, thyrotoxicosis, chronic heart failure, renal failure, azotemia, porphyria, liver failure, congenital deficiency of glucose-6-phosphate dehydrogenase.

Carefully

Children under 3 years of age.

Use during pregnancy and breastfeeding

Contraindicated for use during pregnancy and breastfeeding.

Directions for use and doses

Externally, applied directly to the affected surface; dressings are carried out after 1-2 days. The maximum single dose for adults is 5 g, the maximum daily dose is 15 g. For children over 3 years of age: a single dose is 300 mg, a daily dose is 300 mg.
If there is no improvement after treatment, you should consult a doctor. Use the drug only according to the method of use and in the doses indicated in the instructions. If necessary, please consult your doctor before using the medicine.

Side effect

If you are hypersensitive to sulfonamide drugs, allergic reactions are possible, the development of which requires immediate discontinuation of the drug.
In addition, possible: headache, dizziness, nausea, vomiting, dyspepsia, cyanosis, leukopenia, agranulocytosis, crystalluria.
If any of the side effects listed in the instructions get worse or if any other side effects not listed in the instructions are noticed, tell your doctor.

Overdose

Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, blurred vision, fever, hematuria, crystalluria; with prolonged overdose – thrombocytopenia, leukopenia, megaloblastic anemia, jaundice.
Treatment: drink plenty of fluids; in case of accidental ingestion, gastric lavage.

Interaction with other drugs

Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.
If you are taking other medications (including over-the-counter medications), consult your doctor before using Streptocid.

special instructions

During therapy, it is recommended to drink plenty of alkaline fluids. If necessary, antimicrobial drugs are prescribed orally. During long-term treatment, systematic monitoring of blood counts, liver and kidney function is recommended.

Impact on the ability to drive vehicles and machinery

Studies of the effect of the drug on the reaction rate when driving vehicles or working with other mechanisms have not been conducted.
Considering the side effects of the drug (dizziness), caution should be exercised when driving vehicles or machinery.

Release form

Powder for external use. 2 g or 5 g in heat-sealable bags made of a combined paper-based material or 5 g in a polymer jar with a lid.
1, 2, 5, 10, 20, 50, 100, 200 bags, along with instructions for use, are placed in a plastic film bag.
1, 2, 5, 10, 20, 50, 100, 200 packages along with instructions for use are placed in a cardboard pack.
1, 2, 5, 10, 20, 50, 100, 200 bags, along with instructions for use, are placed in wrapping paper bags.
1 jar along with instructions for use is placed in a cardboard pack.

For hospitals.

1, 2, 5, 10, 20, 50, 100, 200, 600, 1000 bags, along with an equal number of instructions for use, are placed in a plastic film bag.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25°C.
Keep out of the reach of children.

Best before date

5 years. Do not use after expiration date.

Vacation conditions

Available without a prescription.